Rue getting ruthless?

The dynamic between Zendaya and Sydney Sweeney was apparently far from euphoric at the “Euphoria” Season 3 premiere in Los Angeles Tuesday night.

The co-stars avoided each other at the star-studded event — which allegedly came as no surprise to some of their colleagues.

“‘Euphoria’ bosses are all too aware the pair do not get along. There were tensions way back … Their paths barely crossed during the making of Season 3,” an insider alleged to the Sun. “During the press tour, any interactions between the pair are being kept to a minimum to avoid any awkward encounters on camera. There is a complete ban on ­journalists asking about tensions between Zendaya and Sydney.”

A main reason for their alleged feud involves none other than Zendaya’s fiancé, actor Tom Holland.

“It was an open secret that Sydney had the hots for Tom and was flirty with him when he would come to set,” the source claimed. “That did not go down well with Zendaya. They have not really hung out socially since then.”

Zendaya and her “Spider-Man: Homecoming” co-star Holland, both 29, have reportedly tied the knot, but have yet to confirm the news.

Once friendly, Zendaya and Sweeney’s alleged tension appears to have built up over the years. Last month, fans noticed how Sweeney was noticeably missing from a “Euphoria” group photo promoting the new season.

“There will be a sigh of relief when ‘Euphoria’ is over and they can go their separate ways,” the source said of the actresses. “But they both have decades left in Hollywood and this rivalry will inevitably run and run.”

According to the Sun, their political differences have also caused a wedge, as Sweeney is a registered Republican.

“It’s not like they have had a big bust-up, but Zendaya has quietly distanced herself from Syd. Their politics are wildly different,” the insider told the Sun. “It’s a bit of a headache because Zendaya doesn’t want to be associated with a Trump supporter.”

In 2020, Zendaya posted on Instagram, “Vote this MF out,” about President Trump, according to the Sun. Two years later, Sweeney, 28, shared photos from her mom’s 60th hoedown-themed birthday party where guests were decked out in MAGA-style hats.

In July, the “Christy” actress even got a shout-out from Trump after her American Eagle denim partnership caused a stir. Titled “Sydney Sweeney Has Great Jeans,” the campaign sparked a debate about Western beauty standards and “woke culture.”

“Sydney Sweeney, a registered Republican, has the ‘HOTTEST’ ad out there,” Trump wrote on Truth Social at the time. “The jeans are ‘flying off the shelves.’ Go get ’em Sydney!”

Despite the fallout, Sweeney was all smiles while hitting the red carpet at the TCL Chinese Theatre on Tuesday night. She snapped pics with fellow cast members including Maude Apatow, Alexa Demie and Hunter Schafer as they made their way down the interview line.

Zendaya, meanwhile, arrived fashionably late, narrowly avoiding a run-in with Sweeney. Their co-star and a former flame of Zendaya’s, Jacob Elordi, was also late to the carpet, skipping interviews and only posing for photos.

Zendaya also skipped the cast’s official after-party at Chateau Marmont later in the night.

The distance was a striking contrast to when Zendaya and Sweeney posed together at the Season 1 and Season 2 premieres of the HBO series. And Sweeney praised Zendaya’s leadership during an interview with “Access Hollywood” in 2022.

“I’m really lucky because last season I didn’t get to work with her as much,” Sweeney said of the “Euphoria” lead. “It’s been amazing to be able to watch her and to see how much of a boss [she is].”

While Holland stayed home Tuesday night, Sweeney was joined at the premiere by boyfriend Scooter Braun. She and fiancé Jonathan Davino broke up after nearly seven years in March 2025.

Despite Sweeney and Zendaya keeping their distance from each other, an insider close to the situation shut down the report, telling us any rumors of a feud are not accurate.

“They’re both in high demand and working continuously,” the source told Page Six.

Another insider told us that, like Elordi, Zendaya actually missed run-ins with the cast due to her aforementioned late arrival. She arrived much later than Sweeney, Demie, Apatow and Schafer.

Reps for Sweeney and Zendaya did not respond to Page Six’s requests for comment.